Loredano Pollegioni Selected Research

D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)

10/2022	Unveiling the Bio-corona Fingerprinting of Potential Anticancer Carbon Nanotubes Coupled with D-Amino Acid Oxidase.
3/2022	Reactive oxygen species as a double-edged sword: The role of oxidative enzymes in antitumor therapy.
1/2021	An antibody-based enzymatic therapy for cancer treatment: The selective localization of D-amino acid oxidase to EDA fibronectin.
1/2020	PEG-DAAO conjugate: A promising tool for cancer therapy optimized by protein engineering.
11/2017	Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon.
12/2015	High-Throughput Screening Strategy Identifies Allosteric, Covalent Human D-Amino Acid Oxidase Inhibitor.
11/2013	D-amino acid oxidase-nanoparticle system: a potential novel approach for cancer enzymatic therapy.
3/2013	Characterization of human DAAO variants potentially related to an increased risk of schizophrenia.
1/2013	D-amino acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy.
11/2011	Is rat an appropriate animal model to study the involvement of D-serine catabolism in schizophrenia? Insights from characterization of D-amino acid oxidase.

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Loredano Pollegioni Research Topics

Disease

27	Schizophrenia (Dementia Praecox) 01/2022 - 03/2006
14	Neoplasms (Cancer) 10/2022 - 03/2002
10	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2014
7	Mental Disorders (Mental Disorder) 01/2022 - 03/2006
7	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 08/2008
4	Parkinson Disease (Parkinson's Disease) 01/2019 - 04/2013
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 07/2018
3	Brain Diseases (Brain Disorder) 01/2021 - 03/2008
3	Tuberculosis (Tuberculoses) 06/2018 - 11/2014
2	Chronic Renal Insufficiency 01/2022 - 01/2021
2	Nervous System Diseases (Neurological Disorders) 04/2021 - 01/2021
2	Wounds and Injuries (Trauma) 11/2019 - 01/2014
2	Neuroinflammatory Diseases 01/2019 - 01/2018
2	Overactive Urinary Bladder (Overactive Bladder) 11/2017 - 01/2017
2	Pathologic Processes 01/2017 - 08/2012
2	Neoplasm Metastasis (Metastasis) 08/2014 - 03/2002
2	Epilepsy (Aura) 08/2014 - 11/2012
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014 - 08/2012
1	Starvation 03/2022
1	Diabetes Mellitus 01/2022
1	Major Depressive Disorder (Major Depressive Disorders) 01/2022
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022
1	Cognitive Dysfunction 01/2022
1	Microcephaly 12/2020
1	Seizures (Absence Seizure) 12/2020
1	Memory Disorders (Memory Loss) 01/2019
1	Gliosis 01/2019
1	Dyskinesias (Dyskinesia) 01/2019
1	Congenital central hypoventilation syndrome 01/2019
1	Neuralgia (Stump Neuralgia) 11/2018
1	Pain (Aches) 07/2018
1	DiGeorge Syndrome (Syndrome, DiGeorge) 01/2018
1	Synucleinopathies 01/2018
1	Neuroblastoma 10/2017

Drug/Important Bio-Agent (IBA)

27	Serine (L-Serine)FDA Link 01/2022 - 03/2008
17	D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA 10/2022 - 03/2006
17	Proteins (Proteins, Gene)FDA Link 03/2022 - 09/2011
15	EnzymesIBA 10/2022 - 02/2008
13	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021 - 03/2008
10	Amino Acids FDA Link 10/2022 - 01/2012
4	D-Aspartic Acid (D Aspartate)IBA 01/2021 - 01/2017
4	Neurotransmitter Agents (Neurotransmitter)IBA 01/2021 - 09/2011
4	N-Methylaspartate (NMDA)IBA 02/2014 - 03/2008
3	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 10/2022 - 10/2017
3	Proline (L-Proline)FDA Link 01/2022 - 01/2013
3	ProdrugsIBA 01/2021 - 09/2009
3	Glutamic Acid (Glutamate)FDA Link 01/2021 - 01/2013
3	SynucleinsIBA 01/2019 - 04/2013
3	FlavoproteinsIBA 11/2018 - 04/2009
3	VaccinesIBA 06/2018 - 11/2014
3	serine racemaseIBA 01/2017 - 01/2013
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2022 - 03/2022
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2021
2	Messenger RNA (mRNA)IBA 01/2019 - 01/2018
2	GlycoconjugatesIBA 06/2018 - 11/2014
2	Proline Oxidase (Proline Dehydrogenase)IBA 01/2018 - 01/2013
2	Pharmaceutical PreparationsIBA 11/2017 - 01/2017
2	propiverineIBA 11/2017 - 01/2017
2	Antipsychotic Agents (Antipsychotics)IBA 10/2017 - 01/2013
2	Carrier Proteins (Binding Protein)IBA 11/2014 - 03/2002
2	LigandsIBA 08/2010 - 03/2008
1	Carbon Nanotubes (Carbon Nanotube)IBA 10/2022
1	glycolic acid (glycolate)IBA 10/2022
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 10/2022
1	Oxidoreductases (Dehydrogenase)IBA 03/2022
1	Hydroxyl RadicalIBA 03/2022
1	MetalsIBA 03/2022
1	Fibronectins (Fibronectin)IBA 01/2021
1	Peptides (Polypeptides)IBA 01/2021
1	Dopamine (Intropin)FDA LinkGeneric 01/2021
1	Protein Isoforms (Isoforms)IBA 01/2021
1	Heme Oxygenase-1IBA 01/2021
1	F8 monoclonal antibodyIBA 01/2021
1	human RNASET2 proteinIBA 10/2020
1	AlarminsIBA 10/2020
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 10/2020
1	CaspasesIBA 06/2020
1	Superoxides (Superoxide)IBA 06/2020
1	Vancomycin FDA LinkGeneric 11/2019
1	Ciprofloxacin (Cipro)FDA LinkGeneric 11/2019
1	Levodopa (L Dopa)FDA LinkGeneric 01/2019
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2019
1	NBPhox proteinIBA 01/2019
1	polyalanineIBA 01/2019
1	LyasesIBA 12/2018
1	Methionine (L-Methionine)FDA Link 12/2018
1	Arginine (L-Arginine)FDA Link 06/2018
1	alpha-SynucleinIBA 01/2018
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018
1	Glutamine (L-Glutamine)FDA Link 01/2018
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 11/2017
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2017
1	Oxidopamine (6 Hydroxydopamine)IBA 10/2017
1	Olanzapine (Zyprexa)FDA Link 10/2017

Therapy/Procedure

8	Therapeutics 10/2022 - 09/2009
2	Oral Administration 01/2019 - 01/2013
1	Drug Therapy (Chemotherapy) 03/2022
1	Phototherapy (Light Therapy) 03/2022
1	Radiotherapy 03/2022